Ralaniten Sensitizes Enzalutamide-Resistant Prostate Cancer to Ionizing Radiation in Prostate Cancer Cells that Express Androgen Receptor Splice Variants

Blocking androgen receptor (AR) transcriptional activity by androgen deprivation therapy (ADT) improves the response to radiotherapy for intermediate and high risk prostate cancer. Unfortunately, ADT, antiandrogens, and abiraterone increase expression of constitutively active splice variants of AR (...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Banuelos, Carmen A., Ito, Yusuke, Obst, Jon K., Mawji, Nasrin R., Wang, Jun, Hirayama, Yukiyoshi, Leung, Jacky K., Tam, Teresa, Tien, Amy H., Andersen, Raymond J., Sadar, Marianne D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409302/
https://ncbi.nlm.nih.gov/pubmed/32708219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071991
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