Characterization of Niphatenones that Inhibit Androgen Receptor N-Terminal Domain

Androgen ablation therapy causes a temporary reduction in tumor burden in patients with advanced prostate cancer. Unfortunately the malignancy will return to form lethal castration-recurrent prostate cancer (CRPC). The androgen receptor (AR) remains transcriptionally active in CRPC in spite of castr...

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Bibliografiske detaljer
Main Authors: Banuelos, Carmen A., Lal, Aaron, Tien, Amy H., Shah, Neel, Yang, Yu Chi, Mawji, Nasrin R., Meimetis, Labros G., Park, Jacob, Kunzhong, Jian, Andersen, Raymond J., Sadar, Marianne D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182434/
https://ncbi.nlm.nih.gov/pubmed/25268119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107991
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