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Androgen receptor decoy molecules block the growth of prostate cancer

The androgen receptor (AR) is activated by both ligand-dependent and -independent mechanisms. Current therapies for prostate cancer target the ligand-binding domain in the C terminus of the AR. However, ligand-independent activation of the AR occurs by the N-terminal domain (NTD), making the NTD a p...

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Detalhes bibliográficos
Main Authors: Quayle, Steven N., Mawji, Nasrin R., Wang, Jun, Sadar, Marianne D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783142/
https://ncbi.nlm.nih.gov/pubmed/17227854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606718104
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