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Enzalutamide and blocking androgen receptor in advanced prostate cancer: lessons learnt from the history of drug development of antiandrogens

Enzalutamide is a nonsteroidal antiandrogen for the treatment of metastatic castration-resistant prostate cancer (mCRPC) both before and after chemotherapy. Enzalutamide is more effective than its predecessor bicalutamide, which was analyzed in head-to-head studies of patients with CRPC. This family...

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Detalhes bibliográficos
Publicado no:Res Rep Urol
Main Authors: Ito, Yusuke, Sadar, Marianne D
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818862/
https://ncbi.nlm.nih.gov/pubmed/29497605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/RRU.S157116
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