Critical role of androgen receptor level in prostate cancer cell resistance to new generation antiandrogen enzalutamide

Enzalutamide is an androgen receptor (AR) inhibitor approved for therapy of metastatic castration resistant prostate cancer. However, clinical application revealed that 30 to 40% of patients acquire resistance after a short period of treatment. Currently, the molecular mechanisms underlying such res...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Hoefer, Julia, Akbor, Mohammady, Handle, Florian, Ofer, Philipp, Puhr, Martin, Parson, Walther, Culig, Zoran, Klocker, Helmut, Heidegger, Isabel
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312348/
https://ncbi.nlm.nih.gov/pubmed/27486973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10926
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