Targeting the glucocorticoid receptor signature gene Mono Amine Oxidase-A enhances the efficacy of chemo- and anti-androgen therapy in advanced prostate cancer

Despite increasing options for treatment of castration-resistant prostate cancer, development of drug resistance is inevitable. The glucocorticoid receptor (GR) is a prime suspect for acquired therapy resistance, as prostate cancer (PCa) cells are able to increase GR signaling during anti-androgen t...

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Bibliographic Details
Published in:Oncogene
Main Authors: Puhr, Martin, Eigentler, Andrea, Handle, Florian, Hackl, Hubert, Ploner, Christian, Heidegger, Isabel, Schaefer, Georg, Brandt, Maximilian P., Hoefer, Julia, Van der Pluijm, Gabri, Klocker, Helmut
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084733/
https://ncbi.nlm.nih.gov/pubmed/33795839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01754-0
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