Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARγ independent mechanisms

Background/Aims: Thiazolidinediones (TZD) are a new class of oral antidiabetic drugs that have been shown to inhibit growth of some epithelial cancer cells. Although TZD were found to be ligands for peroxisome proliferators activated receptor γ (PPARγ) the mechanism by which TZD exert their anticanc...

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Autores principales: Galli, A, Ceni, E, Crabb, D W, Mello, T, Salzano, R, Grappone, C, Milani, S, Surrenti, E, Surrenti, C, Casini, A
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright 2004 by Gut 2004
Materias:
Pancreas
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774261/
https://ncbi.nlm.nih.gov/pubmed/15479693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.031997
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