Antidiabetic thiazolidinediones induce ductal differentiation but not apoptosis in pancreatic cancer cells

AIM: Thiazolidinediones (TZD) are a new class of oral antidiabetic drugs that have been shown to inhibit growth of same epithelial cancer cells. Although TZD were found to be ligands for peroxisome proliferator-activated receptor γ (PPARγ), the mechanism by which TZD exert their anticancer effect is...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Ceni, Elisabetta, Mello, Tommaso, Tarocchi, Mirko, Crabb, David W, Caldini, Anna, Invernizzi, Pietro, Surrenti, Calogero, Milani, Stefano, Galli, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2005
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250701/
https://ncbi.nlm.nih.gov/pubmed/15754392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i8.1122
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