Fibroblast Growth Factor-21 Regulates PPARγ Activity and the Antidiabetic Actions of Thiazolidinediones

Fibroblast growth factor-21 (FGF21) is a circulating hepatokine that beneficially affects carbohydrate and lipid metabolism. Here we report that FGF21 is also an inducible, fed-state autocrine factor in adipose tissue that functions in a feed-forward loop to regulate the activity of peroxisome proli...

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Bibliografiske detaljer
Main Authors: Dutchak, Paul A., Katafuchi, Takeshi, Bookout, Angie L., Choi, Jang Hyun, Yu, Ruth T., Mangelsdorf, David J., Kliewer, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273727/
https://ncbi.nlm.nih.gov/pubmed/22304921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.11.062
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