Novel Benzylidene Thiazolidinedione Derivatives as Partial PPARγ Agonists and their Antidiabetic Effects on Type 2 Diabetes

Peroxisome proliferator-activated receptor γ (PPARγ) has received significant attention as a key regulator of glucose and lipid homeostasis. In this study, we synthesized and tested a library of novel 5-benzylidene-thiazolidin-2,4-dione (BTZD) derivatives bearing a substituent on nitrogen of TZD nuc...

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Yasmin, Sabina, Capone, Fabio, Laghezza, Antonio, Piaz, Fabrizio Dal, Loiodice, Fulvio, Vijayan, Viswanathan, Devadasan, Velmurugan, Mondal, Susanta K., Atlı, Özlem, Baysal, Merve, Pattnaik, Ashok K., Jayaprakash, Venkatesan, Lavecchia, Antonio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663708/
https://ncbi.nlm.nih.gov/pubmed/29089569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14776-0
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