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PPARγ-Independent Antitumor Effects of Thiazolidinediones

The thiazolidinedione (TZD) family of PPARγ agonists, especially troglitazone and ciglitazone, induce cell cycle arrest, differentiation, and apoptosis in cancer cells. Mounting evidence indicates that TZDs interfere with multiple signaling mechanisms independently of PPARγactivation, which affect m...

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Detalhes bibliográficos
Main Authors: Wei, Shuo, Yang, Jian, Lee, Su-Lin, Kulp, Samuel K., Chen, Ching-Shih
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712818/
https://ncbi.nlm.nih.gov/pubmed/18790559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.08.008
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