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PPARγ-Independent Antitumor Effects of Thiazolidinediones
The thiazolidinedione (TZD) family of PPARγ agonists, especially troglitazone and ciglitazone, induce cell cycle arrest, differentiation, and apoptosis in cancer cells. Mounting evidence indicates that TZDs interfere with multiple signaling mechanisms independently of PPARγactivation, which affect m...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712818/ https://ncbi.nlm.nih.gov/pubmed/18790559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.08.008 |
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