PPARγ-Independent Antitumor Effects of Thiazolidinediones

The thiazolidinedione (TZD) family of PPARγ agonists, especially troglitazone and ciglitazone, induce cell cycle arrest, differentiation, and apoptosis in cancer cells. Mounting evidence indicates that TZDs interfere with multiple signaling mechanisms independently of PPARγactivation, which affect m...

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Bibliographische Detailangaben
Hauptverfasser: Wei, Shuo, Yang, Jian, Lee, Su-Lin, Kulp, Samuel K., Chen, Ching-Shih
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712818/
https://ncbi.nlm.nih.gov/pubmed/18790559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.08.008
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