PPARγ-Independent Antitumor Effects of Thiazolidinediones

The thiazolidinedione (TZD) family of PPARγ agonists, especially troglitazone and ciglitazone, induce cell cycle arrest, differentiation, and apoptosis in cancer cells. Mounting evidence indicates that TZDs interfere with multiple signaling mechanisms independently of PPARγactivation, which affect m...

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Bibliografske podrobnosti
Main Authors: Wei, Shuo, Yang, Jian, Lee, Su-Lin, Kulp, Samuel K., Chen, Ching-Shih
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712818/
https://ncbi.nlm.nih.gov/pubmed/18790559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.08.008
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