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Effects of FXR in Foam-cell Formation and Atherosclerosis Development
Farnesoid X receptor (FXR), a bile-acid-activated transcriptional factor and a member of the hormone nuclear receptor superfamily, is essential in regulating bile-acid, cholesterol, and triglyceride homeostasis. Disruption of the FXR gene in mice results in a proatherosclerotic lipid profile with in...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751860/ https://ncbi.nlm.nih.gov/pubmed/17110163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2006.09.018 |
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