Effects of FXR in Foam-cell Formation and Atherosclerosis Development

Farnesoid X receptor (FXR), a bile-acid-activated transcriptional factor and a member of the hormone nuclear receptor superfamily, is essential in regulating bile-acid, cholesterol, and triglyceride homeostasis. Disruption of the FXR gene in mice results in a proatherosclerotic lipid profile with in...

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Bibliografske podrobnosti
Main Authors: Guo, Grace L., Santamarina-Fojo, Silvia, Akiyama, Taro E., Amar, Marcelo J.A., Paigen, Beverly J., Brewer, Bryan, Gonzalez, Frank J.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751860/
https://ncbi.nlm.nih.gov/pubmed/17110163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2006.09.018
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