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Effects of FXR in Foam-cell Formation and Atherosclerosis Development
Farnesoid X receptor (FXR), a bile-acid-activated transcriptional factor and a member of the hormone nuclear receptor superfamily, is essential in regulating bile-acid, cholesterol, and triglyceride homeostasis. Disruption of the FXR gene in mice results in a proatherosclerotic lipid profile with in...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751860/ https://ncbi.nlm.nih.gov/pubmed/17110163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2006.09.018 |
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