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Enhanced ABCG1 Expression Increases Atherosclerosis in LDLr-KO Mice on a Western Diet
ABCG1 promotes cholesterol efflux from cells, but ABCG1(-/-) bone marrow transplant into ApoE(-/-) and LDLr(-/-) mice reduces atherosclerosis. To further investigate the role of ABCG1 in atherosclerosis, ABCG1 transgenic mice were crossed with LDLr-KO mice and placed on a high-fat western diet. Incr...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847323/ https://ncbi.nlm.nih.gov/pubmed/17070501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.10.044 |
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