The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice

Identification of mutations in the ABCA1 transporter (ABCA1) as the genetic defect in Tangier disease has generated interest in modulating atherogenic risk by enhancing ABCA1 gene expression. To investigate the role of ABCA1 in atherogenesis, we analyzed diet-induced atherosclerosis in transgenic mi...

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Detalhes bibliográficos
Main Authors: Joyce, Charles W., Amar, Marcelo J. A., Lambert, Gilles, Vaisman, Boris L., Paigen, Beverly, Najib-Fruchart, Jamila, Hoyt, Robert F., Neufeld, Edward D., Remaley, Alan T., Fredrickson, Donald S., Brewer, H. Bryan, Santamarina-Fojo, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117573/
https://ncbi.nlm.nih.gov/pubmed/11752403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012587699
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