The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice

Identification of mutations in the ABCA1 transporter (ABCA1) as the genetic defect in Tangier disease has generated interest in modulating atherogenic risk by enhancing ABCA1 gene expression. To investigate the role of ABCA1 in atherogenesis, we analyzed diet-induced atherosclerosis in transgenic mi...

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Detalles Bibliográficos
Autores principales: Joyce, Charles W., Amar, Marcelo J. A., Lambert, Gilles, Vaisman, Boris L., Paigen, Beverly, Najib-Fruchart, Jamila, Hoyt, Robert F., Neufeld, Edward D., Remaley, Alan T., Fredrickson, Donald S., Brewer, H. Bryan, Santamarina-Fojo, Silvia
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2002
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC117573/
https://ncbi.nlm.nih.gov/pubmed/11752403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012587699
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