CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice

OBJECTIVE: Atherosclerosis is a major cause of cardiovascular disease. Monocyte-endothelial cell interactions are partly mediated by expression of monocyte CX3CR1 and endothelial cell fractalkine (CX3CL1). Interrupting the interaction between this ligand–receptor pair should reduce monocyte binding...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Metab
Autori principali: Riopel, Matthew, Vassallo, Melanie, Ehinger, Erik, Pattison, Jennifer, Bowden, Karen, Winkels, Holger, Wilson, Maria, de Jong, Ron, Patel, Sanjay, Balakrishna, Deepika, Bilakovics, James, Fanjul, Andrea, Plonowski, Artur, Larson, Christopher J., Ley, Klaus, Cabrales, Pedro, Witztum, Joseph L., Olefsky, Jerrold M., Lee, Yun Sok
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358552/
https://ncbi.nlm.nih.gov/pubmed/30553772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.11.011
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi