Comparison of HERG channel blocking effects of various β-blockers – implication for clinical strategy

1. β-Blockers are widely used in the treatment of cardiovascular diseases. However, their effects on HERG channels at comparable conditions remain to be defined. We investigated the direct acute effects of β-blockers on HERG current and the molecular basis of drug binding to HERG channels with mutat...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kawakami, Kazunobu, Nagatomo, Toshihisa, Abe, Haruhiko, Kikuchi, Kan, Takemasa, Hiroko, Anson, Blake D, Delisle, Brian P, January, Craig T, Nakashima, Yasuhide
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2005
Materias:
Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751343/
https://ncbi.nlm.nih.gov/pubmed/16314852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706508
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares