Steady-state pharmacokinetics of imipenem in febrile neutropenic cancer patients.

We ascertained the pharmacokinetics of imipenem in febrile granulocytopenic cancer patients. The values observed were both different from and significantly more variable than those observed in normal volunteers. Free drug concentrations exceeded the MIC for 90% of Escherichia coli, Klebsiella pneumo...

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Hauptverfasser: Drusano, G L, Plaisance, K I, Forrest, A, Bustamante, C, Devlin, A, Standiford, H C, Wade, J C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC174953/
https://ncbi.nlm.nih.gov/pubmed/3479047
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