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Pharmacokinetics of imipenem-cilastatin in neonates.

Imipenem and its renal dehydropeptidase I inhibitor, cilastatin, were coadministered intravenously in a 1:1 ratio to 30 newborns. Five infants each received single doses of 10, 15, or 20 mg/kg of both drugs. Concentrations in plasma were proportional to the administered dose, and cilastatin achieved...

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Hlavní autoři: Freij, B J, McCracken, G H, Olsen, K D, Threlkeld, N
Médium: Artigo
Jazyk:Inglês
Vydáno: 1985
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC180068/
https://ncbi.nlm.nih.gov/pubmed/3859242
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