Pharmacokinetics of imipenem-cilastatin in neonates.
Imipenem and its renal dehydropeptidase I inhibitor, cilastatin, were coadministered intravenously in a 1:1 ratio to 30 newborns. Five infants each received single doses of 10, 15, or 20 mg/kg of both drugs. Concentrations in plasma were proportional to the administered dose, and cilastatin achieved...
Zapisane w:
| Wydane w: | Antimicrob Agents Chemother |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
1985
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3859242/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.4.431 |
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