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Pharmacokinetics of imipenem and cilastatin in patients with cystic fibrosis.

The pharmacokinetics of imipenem, a new carbapenem antibiotic, and cilastatin, a metabolic inhibitor, were evaluated in 17 patients with cystic fibrosis. Imipenem and cilastatin were combined in a ratio of 1:1 in the infusion solution, and patients intravenously received 30, 60, or 90 mg of imipenem...

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Detalhes bibliográficos
Main Authors: Reed, M D, Stern, R C, O'Brien, C A, Yamashita, T S, Myers, C M, Blumer, J L
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC180100/
https://ncbi.nlm.nih.gov/pubmed/3859245
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