Pharmacokinetics of imipenem and cilastatin in patients with cystic fibrosis.

The pharmacokinetics of imipenem, a new carbapenem antibiotic, and cilastatin, a metabolic inhibitor, were evaluated in 17 patients with cystic fibrosis. Imipenem and cilastatin were combined in a ratio of 1:1 in the infusion solution, and patients intravenously received 30, 60, or 90 mg of imipenem...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Reed, M D, Stern, R C, O'Brien, C A, Yamashita, T S, Myers, C M, Blumer, J L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180100/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3859245/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.4.583
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