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Steady-state pharmacokinetics of imipenem in febrile neutropenic cancer patients.

We ascertained the pharmacokinetics of imipenem in febrile granulocytopenic cancer patients. The values observed were both different from and significantly more variable than those observed in normal volunteers. Free drug concentrations exceeded the MIC for 90% of Escherichia coli, Klebsiella pneumo...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Drusano, G L, Plaisance, K I, Forrest, A, Bustamante, C, Devlin, A, Standiford, H C, Wade, J C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1987
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3479047/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.9.1420
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