Steady-state pharmacokinetics of imipenem in febrile neutropenic cancer patients.

We ascertained the pharmacokinetics of imipenem in febrile granulocytopenic cancer patients. The values observed were both different from and significantly more variable than those observed in normal volunteers. Free drug concentrations exceeded the MIC for 90% of Escherichia coli, Klebsiella pneumo...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Drusano, G L, Plaisance, K I, Forrest, A, Bustamante, C, Devlin, A, Standiford, H C, Wade, J C
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1987
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174953/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3479047/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.9.1420
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