Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons

Apolipoprotein E (apoE) receptors act as signaling molecules in neurons, altering phosphorylation of numerous proteins after extracellular ligand binding and affecting neurite outgrowth, synapse formation, and neuronal migration. Since apoE is important in the pathogenesis of Alzheimer's diseas...

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Autores principales: Hoe, Hyang-Sook, Freeman, Jacob, Rebeck, G William
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1713232/
https://ncbi.nlm.nih.gov/pubmed/17166269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-18
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