Loading...

Fyn kinase regulates the association between amyloid precursor protein and Dab1 by promoting their localization to detergent-resistant membranes

The adaptor protein Dab1 interacts with amyloid precursor protein (APP) and decreases its pathological processing, an effect mediated by Fyn tyrosine kinase. Fyn is highly enriched in lipid rafts, a major site of pathological APP processing. To investigate the role of Fyn in the localization and pho...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Minami, S. Sakura, Hoe, Hyang-Sook, Rebeck, G. William
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155659/
https://ncbi.nlm.nih.gov/pubmed/21534960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07296.x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!