Nalaganje...
Polo-like kinase 2 phosphorylation of amyloid precursor protein regulates activity-dependent amyloidogenic processing
Alzheimer’s disease (AD) is a neurodegenerative disorder with cognitive deficits. Amyloidogenic processing of amyloid precursor protein (APP) produces amyloid β (Aβ), the major component of hallmark AD plaques. Synaptic activity stimulates APP cleavage, whereas APP promotes excitatory synaptic trans...
Shranjeno v:
| izdano v: | Neuropharmacology |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5414040/ https://ncbi.nlm.nih.gov/pubmed/28257888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.02.027 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|