F-Spondin Interaction with the Apolipoprotein E Receptor ApoEr2 Affects Processing of Amyloid Precursor Protein

A recent study showed that F-spondin, a protein associated with the extracellular matrix, interacted with amyloid precursor protein (APP) and inhibited β-secretase cleavage. F-spondin contains a thrombospondin domain that we hypothesized could interact with the family of receptors for apolipoprotein...

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Bibliografiske detaljer
Main Authors: Hoe, Hyang-Sook, Wessner, David, Beffert, Uwe, Becker, Amanda G., Matsuoka, Yasuji, Rebeck, G. William
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265841/
https://ncbi.nlm.nih.gov/pubmed/16227578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9259-9268.2005
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