The Effects of Amyloid Precursor Protein on Postsynaptic Composition and Activity

The amyloid precursor protein (APP) is cleaved to produce the Alzheimer disease-associated peptide Aβ, but the normal functions of uncleaved APP in the brain are unknown. We found that APP was present in the postsynaptic density of central excitatory synapses and coimmunoprecipitated with N-methyl-d...

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Detaylı Bibliyografya
Asıl Yazarlar: Hoe, Hyang-Sook, Fu, Zhanyan, Makarova, Alexandra, Lee, Ji-Yun, Lu, Congyi, Feng, Li, Pajoohesh-Ganji, Ahdeah, Matsuoka, Yasuji, Hyman, Bradley T., Ehlers, Michael D., Vicini, Stefano, Pak, Daniel T. S., Rebeck, G. William
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2009
Konular:
Mechanisms of Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659208/
https://ncbi.nlm.nih.gov/pubmed/19164281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900141200
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