Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons

Apolipoprotein E (apoE) receptors act as signaling molecules in neurons, altering phosphorylation of numerous proteins after extracellular ligand binding and affecting neurite outgrowth, synapse formation, and neuronal migration. Since apoE is important in the pathogenesis of Alzheimer's diseas...

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Bibliographic Details
Main Authors: Hoe, Hyang-Sook, Freeman, Jacob, Rebeck, G William
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1713232/
https://ncbi.nlm.nih.gov/pubmed/17166269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-18
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