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Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons

Apolipoprotein E (apoE) receptors act as signaling molecules in neurons, altering phosphorylation of numerous proteins after extracellular ligand binding and affecting neurite outgrowth, synapse formation, and neuronal migration. Since apoE is important in the pathogenesis of Alzheimer's diseas...

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Bibliografische gegevens
Hoofdauteurs: Hoe, Hyang-Sook, Freeman, Jacob, Rebeck, G William
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1713232/
https://ncbi.nlm.nih.gov/pubmed/17166269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-18
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