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Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons

Apolipoprotein E (apoE) receptors act as signaling molecules in neurons, altering phosphorylation of numerous proteins after extracellular ligand binding and affecting neurite outgrowth, synapse formation, and neuronal migration. Since apoE is important in the pathogenesis of Alzheimer's diseas...

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Bibliografiske detaljer
Main Authors: Hoe, Hyang-Sook, Freeman, Jacob, Rebeck, G William
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1713232/
https://ncbi.nlm.nih.gov/pubmed/17166269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-18
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