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Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons

Apolipoprotein E (apoE) receptors act as signaling molecules in neurons, altering phosphorylation of numerous proteins after extracellular ligand binding and affecting neurite outgrowth, synapse formation, and neuronal migration. Since apoE is important in the pathogenesis of Alzheimer's diseas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hoe, Hyang-Sook, Freeman, Jacob, Rebeck, G William
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1713232/
https://ncbi.nlm.nih.gov/pubmed/17166269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-18
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