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Crystal structure of NF-κB (p50)(2) complexed to a high-affinity RNA aptamer

We have recently identified an RNA aptamer for the transcription factor NF-κB p50 homodimer [(p50)(2)], which exhibits little sequence resemblance to the consensus DNA target for (p50)(2), but binds (p50)(2) with an affinity similar to that of the optimal DNA target. We describe here the 2.45-Å reso...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Huang, De-Bin, Vu, Don, Cassiday, Laura A., Zimmerman, Jeff M., Maher, L. James, Ghosh, Gourisankar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC170907/
https://ncbi.nlm.nih.gov/pubmed/12886018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1632011100
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