Wird geladen...
Carbocyclic Pyrimidine Nucleosides as Inhibitors of S-Adenosylhomocysteine Hydrolase
The design, synthesis and unexpected inhibitory activity against S-adenosylhomocysteine hydrolase (SAHase) for a series of truncated carbocyclic pyrimidine nucleoside analogues is presented. Of the four nucleosides obtained, 10 was found to be active with a K(i) value of 5.0 μM against SAHase.
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1702506/ https://ncbi.nlm.nih.gov/pubmed/16904326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.07.052 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|