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CARBOCYCLIC THYMIDINE ANALOGUES FOR USE AS POTENTIAL THERAPEUTIC AGENTS
The discovery of azidothymidine’s (AZT) activity against human immunodeficiency virus (HIV) provided strong rationale for the design of additional thymidine analogues. One drawback of many nucleoside analogues is the toxicity that often arises due to phosphorylation by cellular kinases. In order to...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701155/ https://ncbi.nlm.nih.gov/pubmed/20183606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770903091920 |
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