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Synthetic Strategies Toward Carbocyclic Purine-Pyrimidine Hybrid Nucleosides

The blending of key structural features from the purine and pyrimidine nucleobase scaffolds gives rise to a new class of hybrid nucleosides. The purine-pyrimidine hybrid nucleosides can be viewed as either N-3 ribosylated purines or 5,6-disubstituted pyrimidines, thus recognition by both purine- and...

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Détails bibliographiques
Auteurs principaux: Sadler, Joshua M., Mosley, Sylvester L., Dorgan, Kathleen M., Zhou, Zhaohui Sunny, Seley-Radtke, Katherine L.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731674/
https://ncbi.nlm.nih.gov/pubmed/19592260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.06.039
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