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Synthesis of Cyclobutane Analogue 4: Preparation of Purine and Pyrimidine Carbocyclic Nucleoside Derivatives

The coupling of 2-bromo-3-benzoyloxycyclobutanone with purine under basic conditions produces two regioisomers consisting of the N-7 and N-9 alkylated products in equal amounts in their racemic forms. The distribution of the isomers is consistent with the charge delocalization between the N-7 and N-...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Hasaneen, Noha, Ebead, Abdelaziz, Hassan, Muhammad Murtaza, Afifi, Hanan, Hunter, Howard, Lee-Ruff, Edward, El-Gohary, Nadia S., Maarouf, Azza R., El-Emam, Ali A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767184/
https://ncbi.nlm.nih.gov/pubmed/31491981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24183235
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