Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases

Escherichia coli topoisomerase (Topo) IV is an essential type II Topo that removes DNA entanglements created during DNA replication. Topo IV relaxes (+) supercoils much faster than (–) supercoils, promoting replication while sparing the essential (–) supercoils. Here, we investigate the mechanism un...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Stone, Michael D., Bryant, Zev, Crisona, Nancy J., Smith, Steven B., Vologodskii, Alexander, Bustamante, Carlos, Cozzarelli, Nicholas R.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 2003
Θέματα:	Biological Sciences
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166367/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12857958/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1133178100
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