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Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases

Escherichia coli topoisomerase (Topo) IV is an essential type II Topo that removes DNA entanglements created during DNA replication. Topo IV relaxes (+) supercoils much faster than (–) supercoils, promoting replication while sparing the essential (–) supercoils. Here, we investigate the mechanism un...

Täydet tiedot

Tallennettuna:
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Stone, Michael D., Bryant, Zev, Crisona, Nancy J., Smith, Steven B., Vologodskii, Alexander, Bustamante, Carlos, Cozzarelli, Nicholas R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2003
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12857958/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1133178100
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