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RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation
Exposure to short-wavelength UV light (UVC) strongly induces p53 expression. In human RKO colorectal carcinoma cells, this increase was not due to elevated p53 mRNA abundance, cytoplasmic export of p53 mRNA, or UVC-triggered stabilization of the p53 protein. Instead, p53 translation was potently enh...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166233/ https://ncbi.nlm.nih.gov/pubmed/12821781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1432104100 |
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