RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation

Exposure to short-wavelength UV light (UVC) strongly induces p53 expression. In human RKO colorectal carcinoma cells, this increase was not due to elevated p53 mRNA abundance, cytoplasmic export of p53 mRNA, or UVC-triggered stabilization of the p53 protein. Instead, p53 translation was potently enh...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mazan-Mamczarz, Krystyna, Galbán, Stefanie, de Silanes, Isabel López, Martindale, Jennifer L., Atasoy, Ulus, Keene, Jack D., Gorospe , Myriam
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2003
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC166233/
https://ncbi.nlm.nih.gov/pubmed/12821781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1432104100
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