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Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking
Treatment of hyperthyroidism, a common clinical condition that can have serious manifestations in the elderly, has remained essentially unchanged for >30 years. Directly antagonizing the effect of the thyroid hormone at the receptor level may be a significant improvement for the treatment of hype...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165879/ https://ncbi.nlm.nih.gov/pubmed/12777627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1131854100 |
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