Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates

Development of the endocrine pancreas includes a series of early events wherein precursor cells cluster, that is migrate to form cell aggregates, which subsequently differentiate into islets of Langerhans. We show that PANC-1 cells, a human pancreatic cell line, differentiates into hormone-producing...

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Bibliographic Details
Main Authors: Hardikar, Anandwardhan A., Marcus-Samuels, Bernice, Geras-Raaka, Elizabeth, Raaka, Bruce M., Gershengorn, Marvin C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC165839/
https://ncbi.nlm.nih.gov/pubmed/12799459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232230100
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