Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates

Development of the endocrine pancreas includes a series of early events wherein precursor cells cluster, that is migrate to form cell aggregates, which subsequently differentiate into islets of Langerhans. We show that PANC-1 cells, a human pancreatic cell line, differentiates into hormone-producing...

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הוצא לאור ב:	Proc Natl Acad Sci U S A
Principais autores:	Hardikar, Anandwardhan A., Marcus-Samuels, Bernice, Geras-Raaka, Elizabeth, Raaka, Bruce M., Gershengorn, Marvin C.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	National Academy of Sciences 2003
נושאים:	Biological Sciences
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165839/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12799459/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1232230100
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