Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking

Treatment of hyperthyroidism, a common clinical condition that can have serious manifestations in the elderly, has remained essentially unchanged for >30 years. Directly antagonizing the effect of the thyroid hormone at the receptor level may be a significant improvement for the treatment of hyperth...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Schapira, Matthieu, Raaka, Bruce M., Das, Sharmistha, Fan, Li, Totrov, Maxim, Zhou, Zhiguo, Wilson, Stephen R., Abagyan, Ruben, Samuels, Herbert H.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2003
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12777627/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1131854100
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!