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Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine

BACKGROUND: Nicotine is a psychoactive drug presenting a diverse array of biological activities, some positive, such as enhancement of cognitive performances, others negative, such as addiction liability. Ligands that discriminate between the different isotypes of nicotinic acetylcholine receptors (...

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Autors principals: Schapira, Matthieu, Abagyan, Ruben, Totrov, Maxim
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC65631/
https://ncbi.nlm.nih.gov/pubmed/11860617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-2-1
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