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Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine

BACKGROUND: Nicotine is a psychoactive drug presenting a diverse array of biological activities, some positive, such as enhancement of cognitive performances, others negative, such as addiction liability. Ligands that discriminate between the different isotypes of nicotinic acetylcholine receptors (...

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Detalhes bibliográficos
Main Authors: Schapira, Matthieu, Abagyan, Ruben, Totrov, Maxim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC65631/
https://ncbi.nlm.nih.gov/pubmed/11860617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-2-1
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