Načítá se...

Flexible ligand docking to multiple receptor conformations: a practical alternative

State of the art docking algorithms predict an incorrect binding pose for about 50 to 70% of all ligands when only a single fixed receptor conformation is considered. In many more cases, lack of receptor flexibility results in meaningless ligand binding scores, even when the correct pose is obtained...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Totrov, Maxim, Abagyan, Ruben
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396190/
https://ncbi.nlm.nih.gov/pubmed/18302984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2008.01.004
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!