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Structural model of nicotinic acetylcholine receptor isotypes bound to acetylcholine and nicotine

BACKGROUND: Nicotine is a psychoactive drug presenting a diverse array of biological activities, some positive, such as enhancement of cognitive performances, others negative, such as addiction liability. Ligands that discriminate between the different isotypes of nicotinic acetylcholine receptors (...

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Autori principali: Schapira, Matthieu, Abagyan, Ruben, Totrov, Maxim
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC65631/
https://ncbi.nlm.nih.gov/pubmed/11860617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-2-1
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